The majority of big pharma organizations have 3 main pathways for expressing and purifying research quantities of proteins of interest:

• Bacterial (soluble expression),
• Insect / baculovirus
• Mammalian.

Those already collaborating with ProteomTech consider E. coli inclusion bodies a fourth breakthrough pathway.

Pt-Fold offers order of magnitude reduction of cost and time compared to proceeding to insect or mammalian alternatives. Pt-Fold produced proteins have full activity and can be crystallized for high-resolution structure determination.